The Effect of In Vitro Cultivation on the Transcriptome of Adult Brugia malayi
Identifieur interne : 000A58 ( Main/Exploration ); précédent : 000A57; suivant : 000A59The Effect of In Vitro Cultivation on the Transcriptome of Adult Brugia malayi
Auteurs : Cristina Ballesteros [Canada] ; Lucienne Tritten [Canada] ; Maeghan O Eill [Canada] ; Erica Burkman [États-Unis] ; Weam I. Zaky [États-Unis] ; Jianguo Xia [Canada] ; Andrew Moorhead [États-Unis] ; Steven A. Williams [États-Unis] ; Timothy G. Geary [Canada]Source :
- PLoS Neglected Tropical Diseases [ 1935-2727 ] ; 2016.
Abstract
Filarial nematodes cause serious and debilitating infections in human populations of tropical countries, contributing to an entrenched cycle of poverty. Only one human filarial parasite,
Using Illumina RNA sequencing, we characterized changes in gene expression upon
These findings suggest that
Url:
DOI: 10.1371/journal.pntd.0004311
PubMed: 26727204
PubMed Central: 4699822
Affiliations:
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Le document en format XML
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">The Effect of <italic>In Vitro</italic>
Cultivation on the Transcriptome of Adult <italic>Brugia malayi</italic>
</title>
<author><name sortKey="Ballesteros, Cristina" sort="Ballesteros, Cristina" uniqKey="Ballesteros C" first="Cristina" last="Ballesteros">Cristina Ballesteros</name>
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<author><name sortKey="Zaky, Weam I" sort="Zaky, Weam I" uniqKey="Zaky W" first="Weam I." last="Zaky">Weam I. Zaky</name>
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<placeName><region type="state">Massachusetts</region>
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</nlm:aff>
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<wicri:regionArea>Department of Biological Sciences, Smith College, Northampton, Massachusetts</wicri:regionArea>
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<author><name sortKey="Xia, Jianguo" sort="Xia, Jianguo" uniqKey="Xia J" first="Jianguo" last="Xia">Jianguo Xia</name>
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</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Institute of Parasitology, Centre for Host-Parasite Interactions, McGill University, Sainte-Anne-de-Bellevue, Quebec</wicri:regionArea>
<orgName type="university">Université McGill</orgName>
<placeName><settlement type="city">Montréal</settlement>
<region type="state">Québec</region>
</placeName>
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<author><name sortKey="Moorhead, Andrew" sort="Moorhead, Andrew" uniqKey="Moorhead A" first="Andrew" last="Moorhead">Andrew Moorhead</name>
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</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, Georgia</wicri:regionArea>
<placeName><region type="state">Géorgie (États-Unis)</region>
</placeName>
</affiliation>
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<author><name sortKey="Williams, Steven A" sort="Williams, Steven A" uniqKey="Williams S" first="Steven A." last="Williams">Steven A. Williams</name>
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</nlm:aff>
<country xml:lang="fr">États-Unis</country>
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</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Biological Sciences, Smith College, Northampton, Massachusetts</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
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<author><name sortKey="Geary, Timothy G" sort="Geary, Timothy G" uniqKey="Geary T" first="Timothy G." last="Geary">Timothy G. Geary</name>
<affiliation wicri:level="4"><nlm:aff id="aff001"><addr-line>Institute of Parasitology, Centre for Host-Parasite Interactions, McGill University, Sainte-Anne-de-Bellevue, Quebec, Canada</addr-line>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Institute of Parasitology, Centre for Host-Parasite Interactions, McGill University, Sainte-Anne-de-Bellevue, Quebec</wicri:regionArea>
<orgName type="university">Université McGill</orgName>
<placeName><settlement type="city">Montréal</settlement>
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<series><title level="j">PLoS Neglected Tropical Diseases</title>
<idno type="ISSN">1935-2727</idno>
<idno type="eISSN">1935-2735</idno>
<imprint><date when="2016">2016</date>
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<front><div type="abstract" xml:lang="en"><sec id="sec001"><title>Background</title>
<p>Filarial nematodes cause serious and debilitating infections in human populations of tropical countries, contributing to an entrenched cycle of poverty. Only one human filarial parasite, <italic>Brugia malayi</italic>
, can be maintained in rodents in the laboratory setting. It has been a widely used model organism in experiments that employ culture systems, the impact of which on the worms is unknown.</p>
</sec>
<sec id="sec002"><title>Methodology/Principal Findings</title>
<p>Using Illumina RNA sequencing, we characterized changes in gene expression upon <italic>in vitro</italic>
maintenance of adult <italic>B</italic>
. <italic>malayi</italic>
female worms at four time points: immediately upon removal from the host, immediately after receipt following shipment, and after 48 h and 5 days in liquid culture media. The dramatic environmental change and the 24 h time lapse between removal from the host and establishment in culture caused a globally dysregulated gene expression profile. We found a maximum of 562 differentially expressed genes based on pairwise comparison between time points. After an initial shock upon removal from the host and shipping, a few stress fingerprints remained after 48 h in culture and until the experiment was stopped. This was best illustrated by a strong and persistent up-regulation of several genes encoding cuticle collagens, as well as serpins.</p>
</sec>
<sec id="sec003"><title>Conclusions/Significance</title>
<p>These findings suggest that <italic>B</italic>
. <italic>malayi</italic>
can be maintained in culture as a valid system for pharmacological and biological studies, at least for several days after removal from the host and adaptation to the new environment. However, genes encoding several stress indicators remained dysregulated until the experiment was stopped.</p>
</sec>
</div>
</front>
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</author>
<author><name sortKey="Hoerauf, A" uniqKey="Hoerauf A">A Hoerauf</name>
</author>
<author><name sortKey="Bockarie, M" uniqKey="Bockarie M">M Bockarie</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hooper, Pj" uniqKey="Hooper P">PJ Hooper</name>
</author>
<author><name sortKey="Chu, Bk" uniqKey="Chu B">BK Chu</name>
</author>
<author><name sortKey="Mikhailov, A" uniqKey="Mikhailov A">A Mikhailov</name>
</author>
<author><name sortKey="Ottesen, Ea" uniqKey="Ottesen E">EA Ottesen</name>
</author>
<author><name sortKey="Bradley, M" uniqKey="Bradley M">M Bradley</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Krishna Kumari, A" uniqKey="Krishna Kumari A">A Krishna Kumari</name>
</author>
<author><name sortKey="Harichandrakumar, Kt" uniqKey="Harichandrakumar K">KT Harichandrakumar</name>
</author>
<author><name sortKey="Das, Lk" uniqKey="Das L">LK Das</name>
</author>
<author><name sortKey="Krishnamoorthy, K" uniqKey="Krishnamoorthy K">K Krishnamoorthy</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Williams, Sa" uniqKey="Williams S">SA Williams</name>
</author>
<author><name sortKey="Lizotte Waniewski, Mr" uniqKey="Lizotte Waniewski M">MR Lizotte-Waniewski</name>
</author>
<author><name sortKey="Foster, J" uniqKey="Foster J">J Foster</name>
</author>
<author><name sortKey="Guiliano, D" uniqKey="Guiliano D">D Guiliano</name>
</author>
<author><name sortKey="Daub, J" uniqKey="Daub J">J Daub</name>
</author>
<author><name sortKey="Scott, Al" uniqKey="Scott A">AL Scott</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ghedin, E" uniqKey="Ghedin E">E Ghedin</name>
</author>
<author><name sortKey="Wang, S" uniqKey="Wang S">S Wang</name>
</author>
<author><name sortKey="Spiro, D" uniqKey="Spiro D">D Spiro</name>
</author>
<author><name sortKey="Caler, E" uniqKey="Caler E">E Caler</name>
</author>
<author><name sortKey="Zhao, Q" uniqKey="Zhao Q">Q Zhao</name>
</author>
<author><name sortKey="Crabtree, J" uniqKey="Crabtree J">J Crabtree</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Dhar, R" uniqKey="Dhar R">R Dhar</name>
</author>
<author><name sortKey="Sagesser, R" uniqKey="Sagesser R">R Sagesser</name>
</author>
<author><name sortKey="Weikert, C" uniqKey="Weikert C">C Weikert</name>
</author>
<author><name sortKey="Wagner, A" uniqKey="Wagner A">A Wagner</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Telonis Scott, M" uniqKey="Telonis Scott M">M Telonis-Scott</name>
</author>
<author><name sortKey="Clemson, As" uniqKey="Clemson A">AS Clemson</name>
</author>
<author><name sortKey="Johnson, Tk" uniqKey="Johnson T">TK Johnson</name>
</author>
<author><name sortKey="Sgro, Cm" uniqKey="Sgro C">CM Sgro</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Silver, Jt" uniqKey="Silver J">JT Silver</name>
</author>
<author><name sortKey="Noble, Eg" uniqKey="Noble E">EG Noble</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Marioni, Jc" uniqKey="Marioni J">JC Marioni</name>
</author>
<author><name sortKey="Mason, Ce" uniqKey="Mason C">CE Mason</name>
</author>
<author><name sortKey="Mane, Sm" uniqKey="Mane S">SM Mane</name>
</author>
<author><name sortKey="Stephens, M" uniqKey="Stephens M">M Stephens</name>
</author>
<author><name sortKey="Gilad, Y" uniqKey="Gilad Y">Y Gilad</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="O Neill, M" uniqKey="O Neill M">M O'Neill</name>
</author>
<author><name sortKey="Geary, Jf" uniqKey="Geary J">JF Geary</name>
</author>
<author><name sortKey="Agnew, Dw" uniqKey="Agnew D">DW Agnew</name>
</author>
<author><name sortKey="Mackenzie, Cd" uniqKey="Mackenzie C">CD Mackenzie</name>
</author>
<author><name sortKey="Geary, Tg" uniqKey="Geary T">TG Geary</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="O Connell, Em" uniqKey="O Connell E">EM O'Connell</name>
</author>
<author><name sortKey="Bennuru, S" uniqKey="Bennuru S">S Bennuru</name>
</author>
<author><name sortKey="Steel, C" uniqKey="Steel C">C Steel</name>
</author>
<author><name sortKey="Dolan, Ma" uniqKey="Dolan M">MA Dolan</name>
</author>
<author><name sortKey="Nutman, Tb" uniqKey="Nutman T">TB Nutman</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Blankenberg, D" uniqKey="Blankenberg D">D Blankenberg</name>
</author>
<author><name sortKey="Von Kuster, G" uniqKey="Von Kuster G">G Von Kuster</name>
</author>
<author><name sortKey="Coraor, N" uniqKey="Coraor N">N Coraor</name>
</author>
<author><name sortKey="Ananda, G" uniqKey="Ananda G">G Ananda</name>
</author>
<author><name sortKey="Lazarus, R" uniqKey="Lazarus R">R Lazarus</name>
</author>
<author><name sortKey="Mangan, M" uniqKey="Mangan M">M Mangan</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Robinson, Md" uniqKey="Robinson M">MD Robinson</name>
</author>
<author><name sortKey="Mccarthy, Dj" uniqKey="Mccarthy D">DJ McCarthy</name>
</author>
<author><name sortKey="Smyth, Gk" uniqKey="Smyth G">GK Smyth</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Xia, J" uniqKey="Xia J">J Xia</name>
</author>
<author><name sortKey="Gill, Ee" uniqKey="Gill E">EE Gill</name>
</author>
<author><name sortKey="Hancock, Re" uniqKey="Hancock R">RE Hancock</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Xia, J" uniqKey="Xia J">J Xia</name>
</author>
<author><name sortKey="Benner, Mj" uniqKey="Benner M">MJ Benner</name>
</author>
<author><name sortKey="Hancock, Re" uniqKey="Hancock R">RE Hancock</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Anders, S" uniqKey="Anders S">S Anders</name>
</author>
<author><name sortKey="Pyl, Pt" uniqKey="Pyl P">PT Pyl</name>
</author>
<author><name sortKey="Huber, W" uniqKey="Huber W">W Huber</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Robinson, Md" uniqKey="Robinson M">MD Robinson</name>
</author>
<author><name sortKey="Oshlack, A" uniqKey="Oshlack A">A Oshlack</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Robinson, Md" uniqKey="Robinson M">MD Robinson</name>
</author>
<author><name sortKey="Smyth, Gk" uniqKey="Smyth G">GK Smyth</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Benjamini, Y" uniqKey="Benjamini Y">Y Benjamini</name>
</author>
<author><name sortKey="Hochberg, Y" uniqKey="Hochberg Y">Y Hochberg</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Harris, Tw" uniqKey="Harris T">TW Harris</name>
</author>
<author><name sortKey="Lee, R" uniqKey="Lee R">R Lee</name>
</author>
<author><name sortKey="Schwarz, E" uniqKey="Schwarz E">E Schwarz</name>
</author>
<author><name sortKey="Bradnam, K" uniqKey="Bradnam K">K Bradnam</name>
</author>
<author><name sortKey="Lawson, D" uniqKey="Lawson D">D Lawson</name>
</author>
<author><name sortKey="Chen, W" uniqKey="Chen W">W Chen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ashburner, M" uniqKey="Ashburner M">M Ashburner</name>
</author>
<author><name sortKey="Ball, Ca" uniqKey="Ball C">CA Ball</name>
</author>
<author><name sortKey="Blake, Ja" uniqKey="Blake J">JA Blake</name>
</author>
<author><name sortKey="Botstein, D" uniqKey="Botstein D">D Botstein</name>
</author>
<author><name sortKey="Butler, H" uniqKey="Butler H">H Butler</name>
</author>
<author><name sortKey="Cherry, Jm" uniqKey="Cherry J">JM Cherry</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Martin, J" uniqKey="Martin J">J Martin</name>
</author>
<author><name sortKey="Abubucker, S" uniqKey="Abubucker S">S Abubucker</name>
</author>
<author><name sortKey="Wylie, T" uniqKey="Wylie T">T Wylie</name>
</author>
<author><name sortKey="Yin, Y" uniqKey="Yin Y">Y Yin</name>
</author>
<author><name sortKey="Wang, Z" uniqKey="Wang Z">Z Wang</name>
</author>
<author><name sortKey="Mitreva, M" uniqKey="Mitreva M">M Mitreva</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wylie, T" uniqKey="Wylie T">T Wylie</name>
</author>
<author><name sortKey="Martin, Jc" uniqKey="Martin J">JC Martin</name>
</author>
<author><name sortKey="Dante, M" uniqKey="Dante M">M Dante</name>
</author>
<author><name sortKey="Mitreva, Md" uniqKey="Mitreva M">MD Mitreva</name>
</author>
<author><name sortKey="Clifton, Sw" uniqKey="Clifton S">SW Clifton</name>
</author>
<author><name sortKey="Chinwalla, A" uniqKey="Chinwalla A">A Chinwalla</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Xie, C" uniqKey="Xie C">C Xie</name>
</author>
<author><name sortKey="Mao, X" uniqKey="Mao X">X Mao</name>
</author>
<author><name sortKey="Huang, J" uniqKey="Huang J">J Huang</name>
</author>
<author><name sortKey="Ding, Y" uniqKey="Ding Y">Y Ding</name>
</author>
<author><name sortKey="Wu, J" uniqKey="Wu J">J Wu</name>
</author>
<author><name sortKey="Dong, S" uniqKey="Dong S">S Dong</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Livak, Kj" uniqKey="Livak K">KJ Livak</name>
</author>
<author><name sortKey="Schmittgen, Td" uniqKey="Schmittgen T">TD Schmittgen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mccarthy, Dj" uniqKey="Mccarthy D">DJ McCarthy</name>
</author>
<author><name sortKey="Chen, Y" uniqKey="Chen Y">Y Chen</name>
</author>
<author><name sortKey="Smyth, Gk" uniqKey="Smyth G">GK Smyth</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Shin, H" uniqKey="Shin H">H Shin</name>
</author>
<author><name sortKey="Lee, H" uniqKey="Lee H">H Lee</name>
</author>
<author><name sortKey="Fejes, Ap" uniqKey="Fejes A">AP Fejes</name>
</author>
<author><name sortKey="Baillie, Dl" uniqKey="Baillie D">DL Baillie</name>
</author>
<author><name sortKey="Koo, Hs" uniqKey="Koo H">HS Koo</name>
</author>
<author><name sortKey="Jones, Sj" uniqKey="Jones S">SJ Jones</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Choi, Yj" uniqKey="Choi Y">YJ Choi</name>
</author>
<author><name sortKey="Ghedin, E" uniqKey="Ghedin E">E Ghedin</name>
</author>
<author><name sortKey="Berriman, M" uniqKey="Berriman M">M Berriman</name>
</author>
<author><name sortKey="Mcquillan, J" uniqKey="Mcquillan J">J McQuillan</name>
</author>
<author><name sortKey="Holroyd, N" uniqKey="Holroyd N">N Holroyd</name>
</author>
<author><name sortKey="Mayhew, Gf" uniqKey="Mayhew G">GF Mayhew</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Johnstone, Il" uniqKey="Johnstone I">IL Johnstone</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Page, Ap" uniqKey="Page A">AP Page</name>
</author>
<author><name sortKey="Johnstone, Il" uniqKey="Johnstone I">IL Johnstone</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Thompson, Dp" uniqKey="Thompson D">DP Thompson</name>
</author>
<author><name sortKey="Geary, Tg" uniqKey="Geary T">TG Geary</name>
</author>
<author><name sortKey="Marr, Jj" uniqKey="Marr J">JJ Marr</name>
</author>
<author><name sortKey="Komuniecki, R" uniqKey="Komuniecki R">R Komuniecki</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Huntington, Ja" uniqKey="Huntington J">JA Huntington</name>
</author>
<author><name sortKey="Read, Rj" uniqKey="Read R">RJ Read</name>
</author>
<author><name sortKey="Carrell, Rw" uniqKey="Carrell R">RW Carrell</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Silverman, Ga" uniqKey="Silverman G">GA Silverman</name>
</author>
<author><name sortKey="Bird, Pi" uniqKey="Bird P">PI Bird</name>
</author>
<author><name sortKey="Carrell, Rw" uniqKey="Carrell R">RW Carrell</name>
</author>
<author><name sortKey="Church, Fc" uniqKey="Church F">FC Church</name>
</author>
<author><name sortKey="Coughlin, Pb" uniqKey="Coughlin P">PB Coughlin</name>
</author>
<author><name sortKey="Gettins, Pg" uniqKey="Gettins P">PG Gettins</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Yenbutr, P" uniqKey="Yenbutr P">P Yenbutr</name>
</author>
<author><name sortKey="Scott, Al" uniqKey="Scott A">AL Scott</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Zang, X" uniqKey="Zang X">X Zang</name>
</author>
<author><name sortKey="Yazdanbakhsh, M" uniqKey="Yazdanbakhsh M">M Yazdanbakhsh</name>
</author>
<author><name sortKey="Jiang, H" uniqKey="Jiang H">H Jiang</name>
</author>
<author><name sortKey="Kanost, Mr" uniqKey="Kanost M">MR Kanost</name>
</author>
<author><name sortKey="Maizels, Rm" uniqKey="Maizels R">RM Maizels</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Molehin, Aj" uniqKey="Molehin A">AJ Molehin</name>
</author>
<author><name sortKey="Gobert, Gn" uniqKey="Gobert G">GN Gobert</name>
</author>
<author><name sortKey="Mcmanus, Dp" uniqKey="Mcmanus D">DP McManus</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Moreno, Y" uniqKey="Moreno Y">Y Moreno</name>
</author>
<author><name sortKey="Geary, Tg" uniqKey="Geary T">TG Geary</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bennuru, S" uniqKey="Bennuru S">S Bennuru</name>
</author>
<author><name sortKey="Semnani, R" uniqKey="Semnani R">R Semnani</name>
</author>
<author><name sortKey="Meng, Z" uniqKey="Meng Z">Z Meng</name>
</author>
<author><name sortKey="Ribeiro, Jm" uniqKey="Ribeiro J">JM Ribeiro</name>
</author>
<author><name sortKey="Veenstra, Td" uniqKey="Veenstra T">TD Veenstra</name>
</author>
<author><name sortKey="Nutman, Tb" uniqKey="Nutman T">TB Nutman</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Zang, X" uniqKey="Zang X">X Zang</name>
</author>
<author><name sortKey="Atmadja, Ak" uniqKey="Atmadja A">AK Atmadja</name>
</author>
<author><name sortKey="Gray, P" uniqKey="Gray P">P Gray</name>
</author>
<author><name sortKey="Allen, Je" uniqKey="Allen J">JE Allen</name>
</author>
<author><name sortKey="Gray, Ca" uniqKey="Gray C">CA Gray</name>
</author>
<author><name sortKey="Lawrence, Ra" uniqKey="Lawrence R">RA Lawrence</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Maizels, Rm" uniqKey="Maizels R">RM Maizels</name>
</author>
<author><name sortKey="Gomez Escobar, N" uniqKey="Gomez Escobar N">N Gomez-Escobar</name>
</author>
<author><name sortKey="Gregory, Wf" uniqKey="Gregory W">WF Gregory</name>
</author>
<author><name sortKey="Murray, J" uniqKey="Murray J">J Murray</name>
</author>
<author><name sortKey="Zang, X" uniqKey="Zang X">X Zang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Luke, Cj" uniqKey="Luke C">CJ Luke</name>
</author>
<author><name sortKey="Pak, Sc" uniqKey="Pak S">SC Pak</name>
</author>
<author><name sortKey="Askew, Ys" uniqKey="Askew Y">YS Askew</name>
</author>
<author><name sortKey="Naviglia, Tl" uniqKey="Naviglia T">TL Naviglia</name>
</author>
<author><name sortKey="Askew, Dj" uniqKey="Askew D">DJ Askew</name>
</author>
<author><name sortKey="Nobar, Sm" uniqKey="Nobar S">SM Nobar</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Vazquez Mendoza, A" uniqKey="Vazquez Mendoza A">A Vazquez-Mendoza</name>
</author>
<author><name sortKey="Carrero, Jc" uniqKey="Carrero J">JC Carrero</name>
</author>
<author><name sortKey="Rodriguez Sosa, M" uniqKey="Rodriguez Sosa M">M Rodriguez-Sosa</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Engering, A" uniqKey="Engering A">A Engering</name>
</author>
<author><name sortKey="Geijtenbeek, Tb" uniqKey="Geijtenbeek T">TB Geijtenbeek</name>
</author>
<author><name sortKey="Van Kooyk, Y" uniqKey="Van Kooyk Y">Y van Kooyk</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hao, L" uniqKey="Hao L">L Hao</name>
</author>
<author><name sortKey="Johnsen, R" uniqKey="Johnsen R">R Johnsen</name>
</author>
<author><name sortKey="Lauter, G" uniqKey="Lauter G">G Lauter</name>
</author>
<author><name sortKey="Baillie, D" uniqKey="Baillie D">D Baillie</name>
</author>
<author><name sortKey="Burglin, Tr" uniqKey="Burglin T">TR Burglin</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Li, Bw" uniqKey="Li B">BW Li</name>
</author>
<author><name sortKey="Rush, Ac" uniqKey="Rush A">AC Rush</name>
</author>
<author><name sortKey="Mitreva, M" uniqKey="Mitreva M">M Mitreva</name>
</author>
<author><name sortKey="Yin, Y" uniqKey="Yin Y">Y Yin</name>
</author>
<author><name sortKey="Spiro, D" uniqKey="Spiro D">D Spiro</name>
</author>
<author><name sortKey="Ghedin, E" uniqKey="Ghedin E">E Ghedin</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Schlee, M" uniqKey="Schlee M">M Schlee</name>
</author>
<author><name sortKey="Krug, T" uniqKey="Krug T">T Krug</name>
</author>
<author><name sortKey="Gires, O" uniqKey="Gires O">O Gires</name>
</author>
<author><name sortKey="Zeidler, R" uniqKey="Zeidler R">R Zeidler</name>
</author>
<author><name sortKey="Hammerschmidt, W" uniqKey="Hammerschmidt W">W Hammerschmidt</name>
</author>
<author><name sortKey="Mailhammer, R" uniqKey="Mailhammer R">R Mailhammer</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Gordadze, Av" uniqKey="Gordadze A">AV Gordadze</name>
</author>
<author><name sortKey="Peng, R" uniqKey="Peng R">R Peng</name>
</author>
<author><name sortKey="Tan, J" uniqKey="Tan J">J Tan</name>
</author>
<author><name sortKey="Liu, G" uniqKey="Liu G">G Liu</name>
</author>
<author><name sortKey="Sutton, R" uniqKey="Sutton R">R Sutton</name>
</author>
<author><name sortKey="Kempkes, B" uniqKey="Kempkes B">B Kempkes</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bi, P" uniqKey="Bi P">P Bi</name>
</author>
<author><name sortKey="Kuang, S" uniqKey="Kuang S">S Kuang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kurz, Em" uniqKey="Kurz E">EM Kurz</name>
</author>
<author><name sortKey="Holstein, Tw" uniqKey="Holstein T">TW Holstein</name>
</author>
<author><name sortKey="Petri, Bm" uniqKey="Petri B">BM Petri</name>
</author>
<author><name sortKey="Engel, J" uniqKey="Engel J">J Engel</name>
</author>
<author><name sortKey="David, Cn" uniqKey="David C">CN David</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Razin, Sv" uniqKey="Razin S">SV Razin</name>
</author>
<author><name sortKey="Borunova, Vv" uniqKey="Borunova V">VV Borunova</name>
</author>
<author><name sortKey="Maksimenko, Og" uniqKey="Maksimenko O">OG Maksimenko</name>
</author>
<author><name sortKey="Kantidze, Ol" uniqKey="Kantidze O">OL Kantidze</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Gonzalez Montoro, A" uniqKey="Gonzalez Montoro A">A Gonzalez Montoro</name>
</author>
<author><name sortKey="Quiroga, R" uniqKey="Quiroga R">R Quiroga</name>
</author>
<author><name sortKey="Valdez Taubas, J" uniqKey="Valdez Taubas J">J Valdez Taubas</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Li, C" uniqKey="Li C">C Li</name>
</author>
<author><name sortKey="Kim, K" uniqKey="Kim K">K Kim</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Rogers, Cm" uniqKey="Rogers C">CM Rogers</name>
</author>
<author><name sortKey="Franks, Cj" uniqKey="Franks C">CJ Franks</name>
</author>
<author><name sortKey="Walker, Rj" uniqKey="Walker R">RJ Walker</name>
</author>
<author><name sortKey="Burke, Jf" uniqKey="Burke J">JF Burke</name>
</author>
<author><name sortKey="Holden Dye, L" uniqKey="Holden Dye L">L Holden-Dye</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Davis, Re" uniqKey="Davis R">RE Davis</name>
</author>
<author><name sortKey="Stretton, Ao" uniqKey="Stretton A">AO Stretton</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Broadbent, Id" uniqKey="Broadbent I">ID Broadbent</name>
</author>
<author><name sortKey="Pettitt, J" uniqKey="Pettitt J">J Pettitt</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Najarro, Eh" uniqKey="Najarro E">EH Najarro</name>
</author>
<author><name sortKey="Wong, L" uniqKey="Wong L">L Wong</name>
</author>
<author><name sortKey="Zhen, M" uniqKey="Zhen M">M Zhen</name>
</author>
<author><name sortKey="Carpio, Ep" uniqKey="Carpio E">EP Carpio</name>
</author>
<author><name sortKey="Goncharov, A" uniqKey="Goncharov A">A Goncharov</name>
</author>
<author><name sortKey="Garriga, G" uniqKey="Garriga G">G Garriga</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Schmitz, C" uniqKey="Schmitz C">C Schmitz</name>
</author>
<author><name sortKey="Wacker, I" uniqKey="Wacker I">I Wacker</name>
</author>
<author><name sortKey="Hutter, H" uniqKey="Hutter H">H Hutter</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Schmitz, C" uniqKey="Schmitz C">C Schmitz</name>
</author>
<author><name sortKey="Kinge, P" uniqKey="Kinge P">P Kinge</name>
</author>
<author><name sortKey="Hutter, H" uniqKey="Hutter H">H Hutter</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wu, Z" uniqKey="Wu Z">Z Wu</name>
</author>
<author><name sortKey="Ghosh Roy, A" uniqKey="Ghosh Roy A">A Ghosh-Roy</name>
</author>
<author><name sortKey="Yanik, Mf" uniqKey="Yanik M">MF Yanik</name>
</author>
<author><name sortKey="Zhang, Jz" uniqKey="Zhang J">JZ Zhang</name>
</author>
<author><name sortKey="Jin, Y" uniqKey="Jin Y">Y Jin</name>
</author>
<author><name sortKey="Chisholm, Ad" uniqKey="Chisholm A">AD Chisholm</name>
</author>
</analytic>
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<author><name sortKey="Sano, M" uniqKey="Sano M">M Sano</name>
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<author><name sortKey="Goda, S" uniqKey="Goda S">S Goda</name>
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<author><name sortKey="Suzuki, N" uniqKey="Suzuki N">N Suzuki</name>
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<author><name sortKey="Ho, R" uniqKey="Ho R">R Ho</name>
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<author><name sortKey="Cram, Ej" uniqKey="Cram E">EJ Cram</name>
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</author>
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<author><name sortKey="Orrenius, S" uniqKey="Orrenius S">S Orrenius</name>
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</author>
<author><name sortKey="Snoek, Lb" uniqKey="Snoek L">LB Snoek</name>
</author>
<author><name sortKey="De Bono, M" uniqKey="De Bono M">M De Bono</name>
</author>
<author><name sortKey="Kammenga, Je" uniqKey="Kammenga J">JE Kammenga</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Rohlfing, Ak" uniqKey="Rohlfing A">AK Rohlfing</name>
</author>
<author><name sortKey="Miteva, Y" uniqKey="Miteva Y">Y Miteva</name>
</author>
<author><name sortKey="Moronetti, L" uniqKey="Moronetti L">L Moronetti</name>
</author>
<author><name sortKey="He, L" uniqKey="He L">L He</name>
</author>
<author><name sortKey="Lamitina, T" uniqKey="Lamitina T">T Lamitina</name>
</author>
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<region><li>Géorgie (États-Unis)</li>
<li>Massachusetts</li>
<li>Québec</li>
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</settlement>
<orgName><li>Université McGill</li>
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</list>
<tree><country name="Canada"><region name="Québec"><name sortKey="Ballesteros, Cristina" sort="Ballesteros, Cristina" uniqKey="Ballesteros C" first="Cristina" last="Ballesteros">Cristina Ballesteros</name>
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<name sortKey="Xia, Jianguo" sort="Xia, Jianguo" uniqKey="Xia J" first="Jianguo" last="Xia">Jianguo Xia</name>
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<name sortKey="Williams, Steven A" sort="Williams, Steven A" uniqKey="Williams S" first="Steven A." last="Williams">Steven A. Williams</name>
<name sortKey="Williams, Steven A" sort="Williams, Steven A" uniqKey="Williams S" first="Steven A." last="Williams">Steven A. Williams</name>
<name sortKey="Zaky, Weam I" sort="Zaky, Weam I" uniqKey="Zaky W" first="Weam I." last="Zaky">Weam I. Zaky</name>
<name sortKey="Zaky, Weam I" sort="Zaky, Weam I" uniqKey="Zaky W" first="Weam I." last="Zaky">Weam I. Zaky</name>
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